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General Surgery

Management and Optimization of Hemostasis

Antifibrinolytic Agents

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. (opens new window)

Henry DA, Carless PA, Moxey AJ, O'Connell D, Stokes BJ, Fergusson DA, Ker K.

Source‎: Cochrane Database Syst Rev 2011;(3):CD001886.

Indexed‎: PubMed 21412876

DOI‎: 10.1002/14651858.CD001886.pub4

https://www.ncbi.nlm.nih.gov/pubmed/21412876 (opens new window)

Association of intravenous tranexamic acid with thromboembolic events and mortality: a systematic review, meta-analysis, and meta-regression. (opens new window)

Taeuber I, Weibel S, Herrmann E, Neef V, Schlesinger T, Kranke P, Messroghli L, Zacharowski K, Choorapoikayil S, Meybohm P

Source‎: JAMA Surg 2021;156(6):e210884.

Indexed‎: PubMed 33851983

DOI‎: 10.1001/jamasurg.2021.0884

https://www.ncbi.nlm.nih.gov/pubmed/33851983 (opens new window)

Recombinant Activated Factor VII (rFVIIa)

Recombinant factor VIIa as last-resort treatment of desperate haemorrhage. (opens new window)

Palmason R, Vidarsson B, Sigvaldason K, Ingimarsson JP, Gudbjartsson T, Sigurdsson GH, Onundarson PT.

Source‎: Acta Anaesthesiol Scand 2012;56(5):636-44.

Indexed‎: PubMed 22489992

DOI‎: 10.1111/j.1399-6576.2012.02688.x

https://www.ncbi.nlm.nih.gov/pubmed/22489992 (opens new window)

Coagulation Factor Concentrates

Fibrinogen replacement therapy: a critical review of the literature. (opens new window)

Franchini M, Lippi G.

Source‎: Blood Transfus 2012;10(1):23-7.

Indexed‎: PubMed 22153684

DOI‎: 10.2450/2011.0015-11

https://www.ncbi.nlm.nih.gov/pubmed/22153684 (opens new window)

Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy. (opens new window)

Levy JH, Welsby I, Goodnough LT.

Source‎: Transfusion 2014;54(5):1389-405.

Indexed‎: PubMed 24117955

DOI‎: 10.1111/trf.12431

https://www.ncbi.nlm.nih.gov/pubmed/24117955 (opens new window)

Viscoelastic Tests to Identify Surgical or Coagulopathic Bleeding

Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology. (opens new window)

Kozek-Langenecker SA, Afshari A, Albaladejo P, Santullano CA, De Robertis E, Filipescu DC, Fries D, Görlinger K, Haas T, Imberger G, Jacob M, Lancé M, Llau J, Mallett S, Meier J, Rahe-Meyer N, Samama CM, Smith A, Solomon C, Van der Linden P, Wikkelsø AJ, Wouters P, Wyffels P.

Source‎: Eur J Anaesthesiol 2013;30(6):270-382.

Indexed‎: PubMed 23656742

DOI‎: 10.1097/EJA.0b013e32835f4d5b

https://www.ncbi.nlm.nih.gov/pubmed/23656742 (opens new window)

GENERAL SURGERY
Management and Optimization of Hemostasis
English
Management and Optimization of Hemostasis
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A free worldwide service, available 24 hours a day to clinicians treating Jehovah’s Witnesses.

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Medical Information Packets

Subjects include: Clinical strategies for managing hemorrhage and anemia without blood transfusion, the religious and ethical position of Jehovah’s Witnesses on medical therapy, and the services Witnesses offer to the medical community through their worldwide network of Hospital Liaison Committees.

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Videos

Treatment options as well as medical and ethical considerations for clinicians who treat Jehovah’s Witnesses.

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Interview of Alfredo Guglielmi, M.D.

“Jehovah’s Witnesses have led us to be extremely cautious with the use of blood through good patient preparation, careful selection of the patient, careful management in the operating room with all the available blood conservation methods, and management of anemia prior to surgery.”